CLINICAL USES OF 2,3-DIMERCAPTOPROPANOL (BAL). X. THE TREATMENT OF ACUTE SYSTEMIC MERCURY POISONING IN EXPERIMENTAL ANIMALS WITH BAL, THIOSORBITOL AND BAL GLUCOSIDE
نویسندگان
چکیده
منابع مشابه
Clinical Uses of 2,3-dimercaptopropanol (bal). X. the Treatment of Acute Systemic Mercury Poisoning in Experimental Animals with Bal, Thiosorbitol and Bal Glucoside.
Although chemical agents were not employed as offensive weapons during the past war, nevertheless it was imperative to pursue vigorously investigations on the treatment of chemical warfare casualties. Inasmuch as a number of chemical warfare agents contain arsenic, attention was focused on the synthesis of compounds capable of antagonizing the local and systemic effects of arsenical vesicants. ...
متن کاملClinical Uses of 2,3-dimercaptopropanol (bal). Xi. the Treatment of Acute Mercury Poisoning by Bal.
The extensive investigations upon the mechanism by which arsenic poisons the protoplasm of cells (1, 2) and the discovery (1) that the di-thiol, 2,3-dimercaptopropanol or BAL (British AntiLewisite), possesses an avidity for Lewisite and trivalent arsenicals, thus sparing injury to the cells and their essential enzymes, led to the suggestion that the toxic action of other metals might be explain...
متن کاملClinical Uses of 2,3-dimercaptopropanol (bal). X. the Treatment of Acute Systemic Mercury Poisoning
Although chemical agents were not employed as offensive weapons during the past war, nevertheless it was imperative to pursue vigorously investigations on the treatment of chemical warfare casualties. Inasmuch as a number of chemical warfare agents contain arsenic, attention was focused on the synthesis of compounds capable of antagonizing the local and systemic effects of arsenical vesicants. ...
متن کاملClinical Uses of 2,3-dimercaptopropanol (bal). Vii. the Treatment of Arsenical Dermatitis with Preparations of Bal.
The development of 2,3-dimercaptopropanol (British Anti-Lewisite, BAL) by Peters, Stocken, and Thompson (1) has made available a potent antidote for arsenical poisoning. Study of the chemical combination of arsenic with sensitive enzymes and cells indicated that the arsenic could, under certain circumstances, be removed from the cells, and that enzymes could be reactivated by the action of BAL ...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1946
ISSN: 0021-9738
DOI: 10.1172/jci101737